BioConductor

ASSIGN 1.15.3

Adaptive Signature Selection and InteGratioN (ASSIGN)

Released Oct 30, 2014 by Ying Shen

This version is archived for historical reasons. Please see a more recent version for Renjin compatability information.

ASSIGN is a computational tool to evaluate the pathway deregulation/activation status in individual patient samples. ASSIGN employs a flexible Bayesian factor analysis approach that adapts predetermined pathway signatures derived either from knowledge-based literature or from perturbation experiments to the cell-/tissue-specific pathway signatures. The deregulation/activation level of each context-specific pathway is quantified to a score, which represents the extent to which a patient sample encompasses the pathway deregulation/activation signature.

Source

R

Release History