BioConductor

ASSIGN 1.12.0

Adaptive Signature Selection and InteGratioN (ASSIGN)

Released Oct 30, 2014 by Ying Shen, Andrea H. Bild, W. Evan Johnson, and Mumtehena Rahman

This package cannot yet be used with Renjin it depends on other packages which are not available: gplots 3.0.1 and sva 3.24.4

Dependencies

gplots 3.0.1 sva 3.24.4 msm 1.6.4 Rlab 2.15.1

ASSIGN is a computational tool to evaluate the pathway deregulation/activation status in individual patient samples. ASSIGN employs a flexible Bayesian factor analysis approach that adapts predetermined pathway signatures derived either from knowledge-based literatures or from perturbation experiments to the cell-/tissue-specific pathway signatures. The deregulation/activation level of each context-specific pathway is quantified to a score, which represents the extent to which a patient sample encompasses the pathway deregulation/activation signature.

Source

R

Release History