BioConductor
DOSE 3.6.1
Disease Ontology Semantic and Enrichment analysis
This package cannot yet be used with Renjin it depends on other packages which are not available: fgsea 1.6.0 and GOSemSim 2.6.2
An older version of this package is
more compatible with Renjin.
Dependencies
GOSemSim 2.6.2 fgsea 1.6.0 ggplot2 3.0.0 AnnotationDbi 1.42.1 qvalue 2.12.0 BiocParallel 1.14.2 S4Vectors 0.18.3 DO.db 2.9 reshape2 1.4.3
This package implements five methods proposed by Resnik, Schlicker, Jiang, Lin and Wang respectively for measuring semantic similarities among DO terms and gene products. Enrichment analyses including hypergeometric model and gene set enrichment analysis are also implemented for discovering disease associations of high-throughput biological data.