BioConductor
DominoEffect 1.0.0
Identification and Annotation of Protein Hotspot Residues
Released May 1, 2018 by Marija Buljan
This package cannot yet be used with Renjin it depends on other packages which are not available: VariantAnnotation 1.26.1 and data.table 1.11.4
Dependencies
data.table 1.11.4 VariantAnnotation 1.26.1 AnnotationDbi 1.42.1 GenomeInfoDb 1.16.0 Biostrings 2.48.0 GenomicRanges 1.32.6 biomaRt 2.36.1 IRanges 2.14.10 SummarizedExperiment 1.10.1
The functions support identification and annotation of hotspot residues in proteins. These are individual amino acids that accumulate mutations at a much higher rate than their surrounding regions.