BioConductor
DriverNet 1.20.0
Drivernet: uncovering somatic driver mutations modulating transcriptional networks in cancer
Released Mar 21, 2012 by Jiarui Ding
DriverNet is a package to predict functional important driver genes in cancer by integrating genome data (mutation and copy number variation data) and transcriptome data (gene expression data). The different kinds of data are combined by an influence graph, which is a gene-gene interaction network deduced from pathway data. A greedy algorithm is used to find the possible driver genes, which may mutated in a larger number of patients and these mutations will push the gene expression values of the connected genes to some extreme values.
Installation
Maven
This package can be included as a dependency from a Java or Scala project by including
the following your project's pom.xml
file.
Read more
about embedding Renjin in JVM-based projects.
<dependencies> <dependency> <groupId>org.renjin.bioconductor</groupId> <artifactId>DriverNet</artifactId> <version>1.20.0-b1</version> </dependency> </dependencies> <repositories> <repository> <id>bedatadriven</id> <name>bedatadriven public repo</name> <url>https://nexus.bedatadriven.com/content/groups/public/</url> </repository> </repositories>
Renjin CLI
If you're using Renjin from the command line, you load this library by invoking:
library('org.renjin.bioconductor:DriverNet')
Test Results
This package was last tested against Renjin 0.9.2644 on Jun 1, 2018.
- DriverNet-package-examples
- DriverNetResult-class-examples
- actualEvents-examples
- computeDrivers-examples
- computeRandomizedResult-examples
- drivers-examples
- getPatientOutlierMatrix-examples
- preprocessMatrices-examples
- resultSummary-examples
- sampleDriversList-examples
- sampleGeneNames-examples
- sampleInfluenceGraph-examples
- samplePatientExpressionMatrix-examples
- samplePatientMutationMatrix-examples
- samplePatientOutlierMatrix-examples
- sampleRandomDriversResult-examples
- totalEvents-examples