BioConductor

GSVA 1.28.0

Gene Set Variation Analysis for microarray and RNA-seq data

Released Apr 30, 2018 by Justin Guinney

This package cannot yet be used with Renjin it depends on other packages which are not available: shiny 1.1.0 An older version of this package is more compatible with Renjin.

Dependencies

shiny 1.1.0 Biobase 2.40.0 shinythemes 1.1.1 GSEABase 1.42.0 geneplotter 1.58.0 BiocGenerics 0.26.0

Gene Set Variation Analysis (GSVA) is a non-parametric, unsupervised method for estimating variation of gene set enrichment through the samples of a expression data set. GSVA performs a change in coordinate systems, transforming the data from a gene by sample matrix to a gene-set by sample matrix, thereby allowing the evaluation of pathway enrichment for each sample. This new matrix of GSVA enrichment scores facilitates applying standard analytical methods like functional enrichment, survival analysis, clustering, CNV-pathway analysis or cross-tissue pathway analysis, in a pathway-centric manner.