BioConductor
M3D 1.14.0
Identifies differentially methylated regions across testing groups
Released Jun 22, 2016 by Tom Mayo
This package cannot yet be used with Renjin it depends on other packages which are not available: BiSeq 1.20.0
Dependencies
BiSeq 1.20.0 GenomicRanges 1.32.6 BiocGenerics 0.26.0 IRanges 2.14.10 Rcpp S4Vectors 0.18.3 SummarizedExperiment 1.10.1
This package identifies statistically significantly differentially methylated regions of CpGs. It uses kernel methods (the Maximum Mean Discrepancy) to measure differences in methylation profiles, and relates these to inter-replicate changes, whilst accounting for variation in coverage profiles.