BioConductor
TMixClust 1.2.0
Time Series Clustering of Gene Expression with Gaussian Mixed-Effects Models and Smoothing Splines
Released Jun 4, 2017 by Monica Golumbeanu
This package cannot yet be used with Renjin it depends on other packages which are not available: gss 2.1-9
Dependencies
gss 2.1-9 SPEM 1.20.0 Biobase 2.40.0 cluster 2.0.7-1 mvtnorm 1.0-8 zoo 1.8-3 BiocParallel 1.14.2 flexclust 1.3-5
Implementation of a clustering method for time series gene expression data based on mixed-effects models with Gaussian variables and non-parametric cubic splines estimation. The method can robustly account for the high levels of noise present in typical gene expression time series datasets.