BioConductor
YAPSA 1.6.0
Yet Another Package for Signature Analysis
Released Aug 4, 2015 by Daniel Huebschmann
Dependencies
VariantAnnotation 1.26.1 GetoptLong 0.1.7 ComplexHeatmap 1.18.1 SomaticSignatures 2.16.0 dendextend 1.8.0 gtrellis 1.12.1 GenomeInfoDb 1.16.0 circlize 0.4.4 gridExtra 2.3 PMCMR 4.3 KEGGREST 1.20.1 lsei 1.2-0 reshape2 1.4.3 corrplot 0.84 ggplot2 3.0.0 GenomicRanges 1.32.6
This package provides functions and routines useful in the analysis of somatic signatures (cf. L. Alexandrov et al., Nature 2013). In particular, functions to perform a signature analysis with known signatures (LCD = linear combination decomposition) and a signature analysis on stratified mutational catalogue (SMC = stratify mutational catalogue) are provided.