BioConductor
ddgraph 1.20.0
Distinguish direct and indirect interactions with Graphical Modelling
Released Jan 27, 2015 by Robert Stojnic
Dependencies
pcalg 2.6-0 graph 1.58.0 gtools 3.8.1 bnlearn 4.3 RColorBrewer 1.1-2 MASS 7.3-50 Rcpp plotrix 3.7-2
Distinguish direct from indirect interactions in gene regulation and infer combinatorial code from highly correlated variables such as transcription factor binding profiles. The package implements the Neighbourhood Consistent PC algorithm (NCPC) and draws Direct Dependence Graphs to represent dependence structure around a target variable. The package also provides a unified interface to other Graphical Modelling (Bayesian Network) packages for distinguishing direct and indirect interactions.