BioConductor
multtest 2.36.0
Resampling-based multiple hypothesis testing
Released Apr 30, 2018 by Katherine S. Pollard
Dependencies
survival 2.42-6 MASS 7.3-50 Biobase 2.40.0 BiocGenerics 0.26.0
Non-parametric bootstrap and permutation resampling-based multiple testing procedures (including empirical Bayes methods) for controlling the family-wise error rate (FWER), generalized family-wise error rate (gFWER), tail probability of the proportion of false positives (TPPFP), and false discovery rate (FDR). Several choices of bootstrap-based null distribution are implemented (centered, centered and scaled, quantile-transformed). Single-step and step-wise methods are available. Tests based on a variety of t- and F-statistics (including t-statistics based on regression parameters from linear and survival models as well as those based on correlation parameters) are included. When probing hypotheses with t-statistics, users may also select a potentially faster null distribution which is multivariate normal with mean zero and variance covariance matrix derived from the vector influence function. Results are reported in terms of adjusted p-values, confidence regions and test statistic cutoffs. The procedures are directly applicable to identifying differentially expressed genes in DNA microarray experiments.
Installation
Maven
This package can be included as a dependency from a Java or Scala project by including
the following your project's pom.xml
file.
Read more
about embedding Renjin in JVM-based projects.
<dependencies> <dependency> <groupId>org.renjin.bioconductor</groupId> <artifactId>multtest</artifactId> <version>2.36.0-b4</version> </dependency> </dependencies> <repositories> <repository> <id>bedatadriven</id> <name>bedatadriven public repo</name> <url>https://nexus.bedatadriven.com/content/groups/public/</url> </repository> </repositories>
Renjin CLI
If you're using Renjin from the command line, you load this library by invoking:
library('org.renjin.bioconductor:multtest')
Test Results
This package was last tested against Renjin 0.9.2687 on Aug 25, 2018.
- EBMTP-class-examples
- EBMTP-examples
- Hsets-examples
- MTP-class-examples
- MTP-examples
- boot.null-examples
- corr.null-examples
- fwer2gfwer-examples
- get.index-examples
- meanX-examples
- mt.maxT-examples
- mt.plot-examples
- mt.rawp2adjp-examples
- mt.reject-examples
- mt.sample.teststat-examples
- mt.teststat-examples
- ss.maxT-examples
- wapply-examples