BioConductor

nem 2.54.0

(Dynamic) Nested Effects Models and Deterministic Effects Propagation Networks to reconstruct phenotypic hierarchies

Released Apr 30, 2018 by Holger Froehlich

This package cannot yet be used with Renjin it depends on other packages which are not available: Rgraphviz 2.24.0

Dependencies

Rgraphviz 2.24.0 statmod 1.4.30 graph 1.58.0 e1071 1.7-0 RBGL 1.56.0 RColorBrewer 1.1-2 boot 1.3-20 limma 3.36.2 plotrix 3.7-2

The package 'nem' allows to reconstruct features of pathways from the nested structure of perturbation effects. It takes as input (1.) a set of pathway components, which were perturbed, and (2.) phenotypic readout of these perturbations (e.g. gene expression, protein expression). The output is a directed graph representing the phenotypic hierarchy.

Source

R
C

Release History