BioConductor
topdownr 1.2.0
Investigation of Fragmentation Conditions in Top-Down Proteomics
Released May 1, 2018 by Sebastian Gibb
This package cannot yet be used with Renjin it depends on other packages which are not available: MSnbase 2.6.2 and mzR 2.14.0
Dependencies
mzR 2.14.0 MSnbase 2.6.2 ggplot2 3.0.0 Biobase 2.40.0 ProtGenerics 1.12.0 Biostrings 2.48.0 BiocGenerics 0.26.0 S4Vectors 0.18.3 Matrix 1.2-14
The topdownr package allows automatic and systemic investigation of fragment conditions. It creates Thermo Orbitrap Fusion Lumos method files to test hundreds of fragmentation conditions. Additionally it provides functions to analyse and process the generated MS data and determine the best conditions to maximise overall fragment coverage.