Analysis of Codon Data under Stationarity using a Bayesian Framework

Released May 11, 2019 by Cedric Landerer

This package cannot yet be used with Renjin because there was a problem building the package using Renjin's toolchain. View Build Log


Rcpp mvtnorm 1.0-10

Is a collection of models to analyze genome scale codon data using a Bayesian framework. Provides visualization routines and checkpointing for model fittings. Currently published models to analyze gene data for selection on codon usage based on Ribosome Overhead Cost (ROC) are: ROC (Gilchrist et al. (2015) ), and ROC with phi (Wallace & Drummond (2013) ). In addition 'AnaCoDa' contains three currently unpublished models. The FONSE (First order approximation On NonSense Error) model analyzes gene data for selection on codon usage against of nonsense error rates. The PA (PAusing time) and PANSE (PAusing time + NonSense Error) models use ribosome footprinting data to analyze estimate ribosome pausing times with and without nonsense error rate from ribosome footprinting data.