CRAN
GBJ 0.5.2
Generalized Berk-Jones Test for Set-Based Inference in Genetic Association Studies
Released Jun 27, 2018 by Ryan Sun
Dependencies
Rcpp mvtnorm 1.0-8 BH 1.66.0-1 SKAT 1.3.2.1
Offers the Generalized Berk-Jones (GBJ) test for set-based inference in genetic association studies. The GBJ is designed as an alternative to tests such as Berk-Jones (BJ), Higher Criticism (HC), Generalized Higher Criticism (GHC), Minimum p-value (minP), and Sequence Kernel Association Test (SKAT). All of these other methods (except for SKAT) are also implemented in this package, and we additionally provide an omnibus test (OMNI) which integrates information from each of the tests. The GBJ has been shown to outperform other tests in genetic association studies when signals are correlated and moderately sparse. Please see the vignette for a quickstart guide or Sun and Lin (2017)
Installation
Maven
This package can be included as a dependency from a Java or Scala project by including
the following your project's pom.xml
file.
Read more
about embedding Renjin in JVM-based projects.
<dependencies> <dependency> <groupId>org.renjin.cran</groupId> <artifactId>GBJ</artifactId> <version>0.5.2-b1</version> </dependency> </dependencies> <repositories> <repository> <id>bedatadriven</id> <name>bedatadriven public repo</name> <url>https://nexus.bedatadriven.com/content/groups/public/</url> </repository> </repositories>
Renjin CLI
If you're using Renjin from the command line, you load this library by invoking:
library('org.renjin.cran:GBJ')
Test Results
This package was last tested against Renjin 0.9.2657 on Aug 18, 2018.
- BJ-examples
- GBJ-examples
- GBJ_objective-examples
- GBJ_pvalue-examples
- GHC-examples
- GHC_objective-examples
- HC-examples
- OMNI_individual-examples
- OMNI_ss-examples
- calc_score_stats-examples
- calc_var_nonzero_mu-examples
- ebb_loglik-examples
- estimate_ss_cor-examples
- herm_poly_diff_t-examples
- minP-examples
- parse_input-examples
- qnorm_mu-examples
- score_stats_only-examples
- surv-examples
- testthat