CRAN
msarc 1.4.5
Draw Diagrams (mis)Representing the Results of Mass Spec Experiments
Released Jan 27, 2015 by Gord Brown
Dependencies
RColorBrewer 1.1-2 wordcloud 2.5 XLConnect 0.2-15 gplots 3.0.1
The output of an affinity-purification mass spectrometry experiment is typically a list of proteins that were observed in the experiment, identified by UniProt identifiers (http://www.uniprot.org/). This package takes as input a list of UniProt identifiers, and the associated Mascot scores from the experiment (which indicate the likelihood that the protein has been correctly identified), clusters them by gene ontology category (http://geneontology.org/), then draws diagrams showing the results in hierarchical clusters by category, with lines for individual proteins representing the associated Mascot score. The results are in general not publication-ready, but will rather require editing via a graphics editor that can interpret SVG (scalable vector graphics) format. As an alternative representation, the package will also generate tag clouds based on the Mascot scores.