CRAN

nlmixr 1.1.0-9

Nonlinear Mixed Effects Models in Population Pharmacokinetics and Pharmacodynamics

Released May 31, 2019 by Wenping Wang

Dependencies

flextable 0.5.5 tidyr 0.8.3 R.utils 2.9.0 RxODE 0.9.0-8 huxtable 4.6.0 n1qn1 6.0.0-1 stringr 1.4.0 generics 0.0.2 lattice 0.20-38 lbfgsb3c 2018-2.13-1 cli 1.1.0 Rcpp sys 3.2 Matrix 1.2-17 RcppArmadillo 0.9.500.2.0 yaml 2.2.0 minqa 1.2.4 lbfgs 1.2.1 memoise 1.1.0 brew 1.0-6 ggplot2 3.2.0 magrittr 1.5 StanHeaders 2.18.1-10 RcppEigen 0.3.3.5.0 BH 1.69.0-1 digest 0.6.19 fastGHQuad 1.0 nlme 3.1-140 crayon 1.3.4 dparser 0.1.8 vpc 1.0.1 rex 1.1.2

Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 ). Differential equation solving is by compiled C code provided in the 'RxODE' package (Wang, Hallow, and James 2015 ).

Source

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Release History

• 1.1.0-9
• 1.0.0-7
• 0.9.1-3
• 0.9.1-2
• 0.9.1-0
• 0.9.0-3
• 0.9.0-1