CRAN

trialr 0.1.2

Clinical Trial Designs in 'rstan'

Released Jun 25, 2019 by Kristian Brock

Dependencies

tidyr 0.8.3 rstan 2.18.2 tidybayes 1.1.0 purrr 0.3.2 ggplot2 3.2.0 tibble 2.1.3 dplyr 0.8.2 magrittr 1.5 MASS 7.3-51.4 StanHeaders 2.18.1-10 stringr 1.4.0 RcppEigen 0.3.3.5.0 rlang 0.4.0 coda 0.19-2 gtools 3.8.1 Rcpp binom 1.1-1 BH 1.69.0-1 rstantools 1.5.1

A collection of clinical trial designs and methods, implemented in 'rstan' and R, including: the Continual Reassessment Method by O'Quigley et al. (1990) ; EffTox by Thall & Cook (2004) ; and the Augmented Binary method by Wason & Seaman (2013) ; and more. We provide functions to aid model-fitting and analysis. The 'rstan' implementations may also serve as a cookbook to anyone looking to extend or embellish these models. We hope that this package encourages the use of Bayesian methods in clinical trials. There is a preponderance of early phase trial designs because this is where Bayesian methods are used most. If there is a method you would like implemented, please get in touch.

Source

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Release History

• 0.1.2
• 0.1.1
• 0.1.0
• 0.0.7
• 0.0.6
• 0.0.5
• 0.0.4
• 0.0.3
• 0.0.2
• 0.0.1